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S.H.I.E.L.D. is a fictional espionage, special law enforcement, and counter-terrorism agency appearing in American comic books published by Marvel Comics. Created by Stan Lee and Jack Kirby in Strange Tales #135 (Aug. 1965), it often deals with paranormal and superhuman threats.

The acronym originally stood for Supreme Headquarters, International Espionage and Law-Enforcement Division. It was changed in 1991 to Strategic Hazard Intervention Espionage Logistics Directorate. Within the various films set in the Marvel Cinematic Universe, as well as multiple animated and live-action television series, the backronym stands for Strategic Homeland Intervention, Enforcement and Logistics Division.

The organization has heavily appeared in media adaptations as well as films and shows that take place in the Marvel Cinematic Universe.